[4] Penarol 2-0 CA River Plate [6] 2021-03-06 23:15
Stadium: Estadio Campeon del Siglo Round: 11
Referee: Andres Ismael Cunha Soca Home Manager: Mauricio Larriera Away Manager: Jorge Fossati
Head to Head
| Uruguay Torneo Intermedio | 2020/10/17 21:00 | Penarol v CA River Plate | L | 1-2 |
| Uruguay Apertura | 2020/09/09 18:15 | CA River Plate v Penarol | D | 0-0 |
| Uruguay Clausura | 2019/11/09 22:00 | Penarol v CA River Plate | W | 1-0 |
| Uruguay Torneo Intermedio | 2019/08/24 18:00 | CA River Plate v Penarol | L | 1-0 |
| Uruguay Apertura | 2019/05/04 18:00 | CA River Plate v Penarol | W | 0-2 |
| Uruguay Clausura | 2018/07/29 18:00 | CA River Plate v Penarol | W | 0-1 |
| Uruguay Torneo Intermedio | 2018/05/20 22:00 | Penarol v CA River Plate | W | 6-0 |
| Uruguay Apertura | 2018/02/11 22:30 | Penarol v CA River Plate | W | 4-1 |
| Uruguay Clausura | 2017/11/22 20:00 | CA River Plate v Penarol | L | 2-1 |
| Uruguay Apertura | 2017/04/29 22:00 | Penarol v CA River Plate | D | 1-1 |
| Uruguay Apertura | 2016/12/03 19:30 | CA River Plate v Penarol | L | 3-1 |
| Uruguay Clausura | 2016/04/03 21:00 | Penarol v CA River Plate | L | 0-2 |
| Uruguay Apertura | 2015/09/27 21:30 | CA River Plate v Penarol | L | 4-0 |
| Uruguay Clausura | 2015/04/05 19:00 | CA River Plate v Penarol | W | 1-2 |
| Uruguay Apertura | 2014/09/28 21:30 | Penarol v CA River Plate | W | 3-1 |