Head to Head
| Uruguay Clausura | 2022/09/04 18:30 | Nacional De Football v Penarol | W | 3-1 |
| Uruguay Apertura | 2022/02/27 20:00 | Penarol v Nacional De Football | L | 1-0 |
| Club Friendly List | 2022/01/26 22:00 | Penarol v Nacional De Football | L | 1-0 |
| Uruguay Clausura | 2021/10/31 19:00 | Penarol v Nacional De Football | D | 0-0 |
| Copa Sudamericana | 2021/07/23 00:30 | Penarol v Nacional De Football | W | 0-1 |
| Copa Sudamericana | 2021/07/16 00:30 | Nacional De Football v Penarol | L | 1-2 |
| Uruguay Apertura | 2021/07/04 19:00 | Nacional De Football v Penarol | W | 2-0 |
| Uruguay Clausura | 2021/02/03 21:30 | Penarol v Nacional De Football | D | 0-0 |
Home History
| Club Friendly List | 2023/01/17 00:30 | Nacional De Football v Belgrano | L | 4-6 |
| Club Friendly List | 2023/01/15 00:30 | Nacional De Football v Colon | L | 5-6 |
| Club Friendly List | 2023/01/12 00:30 | Nacional De Football v Velez Sarsfield | L | 1-3 |
| Uruguay Clausura | 2022/10/30 19:00 | Liverpool Montevideo v Nacional De Football | W | 1-4 |
| Uruguay Clausura | 2022/10/23 22:30 | Nacional De Football v Danubio | W | 2-0 |
| Uruguay Clausura | 2022/10/17 23:30 | Cerrito v Nacional De Football | W | 1-2 |
| Uruguay Clausura | 2022/10/13 22:00 | Albion FC v Nacional De Football | W | 0-1 |
| Uruguay Clausura | 2022/10/08 22:30 | Nacional De Football v Defensor Sporting | D | 1-1 |
Away History
| Club Friendly List | 2023/01/21 00:30 | Penarol v Union Santa Fe | L | 8-9 |
| Club Friendly List | 2023/01/17 23:00 | Penarol v San Lorenzo | W | 1-0 |
| Club Friendly List | 2023/01/13 00:30 | Penarol v Estudiantes LP | W | 3-2 |
| Uruguay Cup | 2022/11/01 23:00 | La Luz v Penarol | L | 5-2 |
| Uruguay Cup | 2022/10/27 23:00 | Penarol v La Luz | W | 1-0 |
| Uruguay Clausura | 2022/10/22 22:00 | Cerro Largo v Penarol | W | 0-2 |
| Uruguay Clausura | 2022/10/16 21:30 | Penarol v CA River Plate | D | 1-1 |
| Uruguay Clausura | 2022/10/12 22:00 | Boston River v Penarol | L | 2-1 |