Stadium: HTC Center
Home Manager: Steve Donahue Away Manager: Jeff Jones
| NCAAB | 2021/11/20 00:30 | East Carolina v Old Dominion | L | 73-60 |
| NCAAB | 2021/11/19 02:00 | Indiana State v Old Dominion | L | 77-36 |
| NCAAB | 2021/11/16 00:00 | Manhattan v Old Dominion | W | 58-79 |
| NCAAB | 2021/11/13 21:00 | Old Dominion v James Madison | L | 53-58 |
| NCAAB | 2021/11/11 00:00 | Old Dominion v Virginia Wesleyan | W | 80-60 |
| NCAAB | 2021/03/12 03:00 | North Texas v Old Dominion | L | 61-55 |
| NCAAB | 2021/03/06 22:00 | Old Dominion v Western Kentucky | L | 57-60 |
| NCAAB | 2021/03/06 01:00 | Old Dominion v Western Kentucky | W | 71-69 |
| NCAAB | 2021/11/19 19:30 | Davidson v Pennsylvania | L | 72-60 |
| NCAAB | 2021/11/18 19:30 | Pennsylvania v Utah State | L | 79-87 |
| NCAAB | 2021/11/17 00:00 | Lafayette v Pennsylvania | W | 57-85 |
| NCAAB | 2021/11/14 19:00 | Pennsylvania v Bucknell | W | 73-68 |
| NCAAB | 2021/11/13 00:00 | Pennsylvania v George Mason | L | 66-87 |
| NCAAB | 2021/11/11 02:00 | Pennsylvania v Florida State | L | 70-105 |
| NCAAB | 2021/10/30 21:00 | Pennsylvania v East Stroudsburg | W | 91-83 |
| NCAAB | 2020/03/07 23:00 | Columbia v Pennsylvania | W | 65-85 |