Stadium: Reitz Arena
Home Manager: Tavaras Hardy Away Manager: Fran O'Hanlon
| NCAAB | 2021/02/14 22:00 | Lafayette v Loyola Maryland | L | 69-88 |
| NCAAB | 2021/02/13 19:00 | Loyola Maryland v Lafayette | W | 94-97 |
| NCAAB | 2021/02/09 00:00 | Loyola Maryland v Lafayette | W | 76-80 |
| NCAAB | 2021/02/07 17:00 | Lafayette v Loyola Maryland | L | 62-75 |
| NCAAB | 2021/01/17 23:00 | Lafayette v Loyola Maryland | W | 72-70 |
| NCAAB | 2021/01/16 21:00 | Loyola Maryland v Lafayette | W | 75-77 |
| NCAAB | 2020/02/23 19:00 | Loyola Maryland v Lafayette | L | 70-68 |
| NCAAB | 2020/01/11 18:00 | Lafayette v Loyola Maryland | W | 65-62 |
| NCAAB | 2022/01/11 00:00 | Navy v Lafayette | L | 69-55 |
| NCAAB | 2022/01/08 00:00 | Lafayette v Holy Cross | L | 74-79 |
| NCAAB | 2021/12/23 00:00 | Lafayette v Gwynedd Mercy | W | 87-66 |
| NCAAB | 2021/12/11 19:00 | Princeton v Lafayette | L | 84-73 |
| NCAAB | 2021/12/09 00:00 | Lafayette v Delaware | L | 58-68 |
| NCAAB | 2021/12/05 19:00 | NJIT v Lafayette | L | 90-86 |
| NCAAB | 2021/12/03 00:00 | Sacred Heart v Lafayette | L | 74-67 |
| NCAAB | 2021/11/30 00:00 | Lafayette v Columbia | W | 73-50 |
| NCAAB | 2022/01/11 00:00 | Bucknell v Loyola Maryland | W | 67-71 |
| NCAAB | 2022/01/07 22:00 | Loyola Maryland v Boston U | W | 66-58 |
| NCAAB | 2022/01/05 00:00 | Holy Cross v Loyola Maryland | W | 70-79 |
| NCAAB | 2022/01/01 19:00 | Loyola Maryland v Army | L | 74-77 |
| NCAAB | 2021/12/12 19:00 | Hampton v Loyola Maryland | W | 54-67 |
| NCAAB | 2021/12/09 00:00 | Loyola Maryland v St. Bonaventure | L | 71-84 |
| NCAAB | 2021/12/04 18:00 | Mount St Marys v Loyola Maryland | W | 55-61 |
| NCAAB | 2021/12/02 00:00 | Chicago St v Loyola Maryland | W | 64-78 |