| Argentina Reserve League | 2021/08/27 18:00 | Godoy Cruz Reserves v Deportivo Rodeo Del Medio Reserves | L | 1-2 |
| Argentina Reserve League | 2021/10/24 12:00 | Godoy Cruz Reserves v Banfield Reserves | W | 2-0 |
| Argentina Reserve League | 2021/10/19 13:00 | Boca Juniors Reserves v Godoy Cruz Reserves | L | 6-0 |
| Argentina Reserve League | 2021/10/15 12:00 | Godoy Cruz Reserves v Central Cordoba SdE Reserves | W | 3-0 |
| Argentina Regional League | 2021/10/11 13:00 | Godoy Cruz Reserves v CD Rivadavia | D | 2-2 |
| Argentina Reserve League | 2021/10/07 13:00 | Arsenal de Sarandi Reserves v Godoy Cruz Reserves | L | 2-0 |
| Argentina Reserve League | 2021/10/01 15:00 | Godoy Cruz Reserves v Newell's Reserves | D | 1-1 |
| Argentina Reserve League | 2021/09/23 13:00 | CA Independiente Reserves v Godoy Cruz Reserves | D | 0-0 |
| Argentina Regional League | 2021/09/20 18:00 | Godoy Cruz Reserves v CA Fray Luis Beltran | W | 4-1 |
| Argentina Reserve League | 2021/08/27 18:00 | Godoy Cruz Reserves v Deportivo Rodeo Del Medio Reserves | W | 1-2 |