[3] TB Lightning 5-3 OTT Senators [6] 2021-11-06 18:00
Stadium: Canadian Tire Centre
Home Manager: Away Manager: Jon Cooper
Head to Head
| NHL | 2020/01/05 00:00 | TB Lightning v OTT Senators | W | 5-3 |
| NHL | 2019/12/18 00:00 | OTT Senators v TB Lightning | W | 3-4 |
| NHL | 2019/10/12 20:00 | TB Lightning v OTT Senators | L | 2-4 |
| NHL | 2019/04/01 23:30 | TB Lightning v OTT Senators | W | 5-2 |
| NHL | 2019/03/03 00:00 | OTT Senators v TB Lightning | W | 1-5 |
| NHL | 2018/11/11 00:00 | OTT Senators v TB Lightning | L | 6-4 |
| NHL | 2018/11/05 00:00 | TB Lightning v OTT Senators | W | 4-3 |
| NHL | 2018/03/13 23:30 | OTT Senators v TB Lightning | L | 7-4 |
Home History
| NHL | 2021/11/04 23:00 | TB Lightning v TOR Maple Leafs | L | 1-2 |
| NHL | 2021/11/01 23:00 | WAS Capitals v TB Lightning | W | 2-3 |
| NHL | 2021/10/28 23:00 | ARZ Coyotes v TB Lightning | W | 1-5 |
| NHL | 2021/10/26 23:00 | TB Lightning v PIT Penguins | W | 5-1 |
| NHL | 2021/10/25 23:00 | TB Lightning v BUF Sabres | L | 1-5 |
| NHL | 2021/10/23 23:00 | COL Avalanche v TB Lightning | L | 4-3 |
| NHL | 2021/10/19 23:00 | FLA Panthers v TB Lightning | L | 4-1 |
| NHL | 2021/10/16 23:00 | TB Lightning v WAS Capitals | W | 2-1 |
Away History
| NHL | 2021/11/04 23:00 | VGS Golden Knights v OTT Senators | L | 5-1 |
| NHL | 2021/11/03 00:00 | OTT Senators v MIN Wild | L | 4-5 |
| NHL | 2021/11/02 00:00 | OTT Senators v CHI Blackhawks | L | 1-5 |
| NHL | 2021/10/30 00:30 | OTT Senators v DAL Stars | W | 4-1 |
| NHL | 2021/10/25 23:00 | WAS Capitals v OTT Senators | L | 7-5 |
| NHL | 2021/10/23 17:00 | NY Rangers v OTT Senators | L | 3-2 |
| NHL | 2021/10/21 23:00 | SJ Sharks v OTT Senators | L | 2-1 |
| NHL | 2021/10/17 21:00 | DAL Stars v OTT Senators | W | 2-3 |