[7] Union Espanola 2-1 La Serena [11] 2021-09-25 18:00
Stadium: Estadio Santa Laura Round: 22
Referee: Cristian Droguett Home Manager: Cesar Bravo Away Manager: Miguel Ponce
Head to Head
| Chile Primera Division | 2021/04/24 19:30 | La Serena v Union Espanola | D | 0-0 |
| Chile Primera Division | 2021/02/10 21:30 | Union Espanola v La Serena | D | 1-1 |
| Chile Primera Division | 2020/10/03 14:00 | La Serena v Union Espanola | W | 0-2 |
| World Club Friendlies | 2017/01/17 23:30 | La Serena v Union Espanola | W | 1-2 |
Home History
| Chile Primera Division | 2021/09/13 22:00 | Union Espanola v Universidad de Chile | L | 2-3 |
| Chile Primera Division | 2021/09/07 18:00 | Melipilla v Union Espanola | W | 0-3 |
| Chile Cup | 2021/09/01 23:00 | Union Espanola v Colo Colo | L | 2-3 |
| Chile Primera Division | 2021/08/29 23:00 | Union Espanola v Union La Calera | W | 2-1 |
| Chile Primera Division | 2021/08/26 20:30 | Santiago Wanderers v Union Espanola | W | 1-2 |
| Chile Primera Division | 2021/08/22 15:00 | Cobresal v Union Espanola | L | 2-0 |
| Chile Cup | 2021/08/18 21:00 | Colo Colo v Union Espanola | L | 4-0 |
| Chile Primera Division | 2021/08/14 20:30 | Union Espanola v Colo Colo | L | 0-1 |
Away History
| Chile Primera Division | 2021/09/14 17:00 | La Serena v O'Higgins | W | 2-0 |
| Chile Primera Division | 2021/09/06 23:00 | Universidad de Chile v La Serena | D | 1-1 |
| Chile Primera Division | 2021/08/31 01:00 | Curico Unido v La Serena | L | 2-0 |
| Chile Primera Division | 2021/08/26 18:00 | La Serena v Audax Italiano | L | 0-2 |
| Chile Primera Division | 2021/08/21 15:30 | Santiago Wanderers v La Serena | D | 2-2 |
| Chile Primera Division | 2021/08/14 18:00 | La Serena v Union La Calera | L | 1-2 |
| Chile Primera Division | 2021/08/08 00:00 | Universidad Catolica v La Serena | L | 4-3 |
| Chile Primera Division | 2021/08/02 18:30 | La Serena v CD Antofagasta | D | 1-1 |