[3] Nacional Asuncion 1-3 Guairena FC [5] 2021-04-30 22:00
Stadium: Estadio Arsenio Erico Round: 14
Referee: Giancarlos Juliadoza Home Manager: Hernan Rodrigo Lopez Mora Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay Division Profesional | 2021/03/01 21:30 | Guairena FC v Nacional Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/11/22 21:30 | Nacional Asuncion v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2020/08/07 20:00 | Guairena FC v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2020/01/18 21:00 | Nacional Asuncion v Guairena FC | W | 3-0 |
Home History
| Paraguay Division Profesional | 2021/04/26 00:00 | Libertad Asuncion v Nacional Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2021/04/17 21:45 | Nacional Asuncion v Sportivo Luqueno | W | 1-0 |
| Paraguay Division Profesional | 2021/04/10 22:15 | Sol de America v Nacional Asuncion | W | 1-2 |
| Copa Sudamericana | 2021/04/06 22:15 | Nacional Asuncion v 12 de Octubre | L | 4-5 |
| Paraguay Division Profesional | 2021/04/02 00:30 | Nacional Asuncion v Guarani Asuncion | W | 2-0 |
| Paraguay Division Profesional | 2021/03/20 22:00 | Nacional Asuncion v 12 de Octubre | D | 1-1 |
| Copa Sudamericana | 2021/03/16 22:15 | 12 de Octubre v Nacional Asuncion | D | 0-0 |
| Paraguay Division Profesional | 2021/03/13 21:30 | River Plate Asuncion v Nacional Asuncion | D | 0-0 |
Away History
| Paraguay Division Profesional | 2021/04/25 21:45 | Guairena FC v Cerro Porteno | L | 0-1 |
| Paraguay Division Profesional | 2021/04/16 22:00 | Guairena FC v Olimpia Asuncion | L | 1-2 |
| Paraguay Division Profesional | 2021/04/12 00:30 | Libertad Asuncion v Guairena FC | L | 2-1 |
| Copa Sudamericana | 2021/04/08 22:15 | River Plate Asuncion v Guairena FC | L | 4-2 |
| Paraguay Division Profesional | 2021/04/03 22:15 | Guairena FC v Sportivo Luqueno | W | 3-0 |
| Paraguay Division Profesional | 2021/03/22 21:15 | Guairena FC v Sol de America | D | 2-2 |
| Copa Sudamericana | 2021/03/18 22:15 | Guairena FC v River Plate Asuncion | L | 1-2 |
| Paraguay Division Profesional | 2021/03/14 20:45 | Guarani Asuncion v Guairena FC | W | 0-3 |