[16] Atletico San Luis 1-4 Puebla [4] 2021-04-17 22:00
Stadium: Alfonso Lastras Ramirez Round: 15
Referee: Cesar Arturo Ramos Palazuelos Home Manager: Leonel Rocco Away Manager: Nicolas Larcamon
Head to Head
| Mexico Liga MX | 2020/11/07 01:30 | Puebla v Atletico San Luis | L | 1-0 |
| Mexico Liga MX | 2020/03/14 23:00 | Atletico San Luis v Puebla | L | 0-1 |
| Mexico Liga MX | 2019/09/14 00:00 | Puebla v Atletico San Luis | W | 1-3 |
Home History
| Mexico Liga MX | 2021/04/10 02:30 | Juarez FC v Atletico San Luis | L | 2-1 |
| Mexico Liga MX | 2021/04/04 03:06 | Monterrey v Atletico San Luis | L | 2-0 |
| Mexico Liga MX | 2021/03/20 23:00 | Atletico San Luis v Unam Pumas | L | 0-1 |
| Mexico Liga MX | 2021/03/15 00:00 | Queretaro v Atletico San Luis | L | 2-1 |
| Mexico Liga MX | 2021/03/06 01:30 | Atletico San Luis v Toluca | D | 0-0 |
| Mexico Liga MX | 2021/03/02 23:00 | Atlas v Atletico San Luis | L | 3-1 |
| Mexico Liga MX | 2021/02/26 03:00 | Atletico San Luis v Tigres UANL | D | 2-2 |
| Mexico Liga MX | 2021/02/19 03:00 | Atletico San Luis v Santos Laguna | W | 1-0 |
Away History
| Mexico Liga MX | 2021/04/13 02:00 | Pachuca v Puebla | W | 1-3 |
| Mexico Liga MX | 2021/04/03 01:30 | Puebla v Mazatlan FC | W | 3-1 |
| Mexico Liga MX | 2021/03/21 18:00 | Toluca v Puebla | D | 4-4 |
| Mexico Liga MX | 2021/03/13 01:30 | Puebla v Atlas | L | 0-1 |
| Mexico Liga MX | 2021/03/06 03:30 | Puebla v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2021/03/03 03:00 | Leon v Puebla | W | 1-2 |
| Mexico Liga MX | 2021/02/27 01:30 | Puebla v Necaxa | W | 1-0 |
| Mexico Liga MX | 2021/02/21 23:00 | Queretaro v Puebla | D | 1-1 |